TY - JOUR
T1 - Probiotics and Plant-Based Foods as Preventive Agents of Urinary Tract Infection
T2 - A Narrative Review of Possible Mechanisms Related to Health
AU - Saraiva, Ariana
AU - Raheem, Dele
AU - Roy, Poly Rani
AU - BinMowyna, Mona N.
AU - Romão, Bernardo
AU - Alarifi, Sehad N.
AU - Albaridi, Najla A.
AU - Alsharari, Zayed D.
AU - Raposo, António
N1 - Publisher Copyright:
© 2025 by the authors.
PY - 2025/3
Y1 - 2025/3
N2 - Urinary tract infections (UTIs) are a prevalent global health issue, often requiring antibiotic treatment, which contributes to antimicrobial resistance. This narrative review explores the potential of probiotics and plant-based foods as alternative or complementary preventive strategies against UTIs. Fermented foods, such as yogurt, kefir, and kombucha, contain probiotic strains that can modulate the gut and urogenital microbiota, enhancing resistance to uropathogens. Likewise, plant-based foods, including cranberry, garlic, bearberry, juniper, and nettle, possess bioactive compounds with antimicrobial, anti-inflammatory, and diuretic properties. Laboratory and clinical studies suggest that these natural interventions may reduce the incidence of UTIs by inhibiting pathogen adhesion, modulating immune responses, and promoting urinary tract health. However, despite promising findings, inconsistencies in study methodologies, dosage standardization, and long-term efficacy warrant further investigation. Future research should focus on optimizing probiotic formulations, standardizing plant-based supplement dosages, and assessing potential food–drug interactions to establish evidence-based guidelines for UTI prevention.
AB - Urinary tract infections (UTIs) are a prevalent global health issue, often requiring antibiotic treatment, which contributes to antimicrobial resistance. This narrative review explores the potential of probiotics and plant-based foods as alternative or complementary preventive strategies against UTIs. Fermented foods, such as yogurt, kefir, and kombucha, contain probiotic strains that can modulate the gut and urogenital microbiota, enhancing resistance to uropathogens. Likewise, plant-based foods, including cranberry, garlic, bearberry, juniper, and nettle, possess bioactive compounds with antimicrobial, anti-inflammatory, and diuretic properties. Laboratory and clinical studies suggest that these natural interventions may reduce the incidence of UTIs by inhibiting pathogen adhesion, modulating immune responses, and promoting urinary tract health. However, despite promising findings, inconsistencies in study methodologies, dosage standardization, and long-term efficacy warrant further investigation. Future research should focus on optimizing probiotic formulations, standardizing plant-based supplement dosages, and assessing potential food–drug interactions to establish evidence-based guidelines for UTI prevention.
KW - antimicrobial resistance
KW - bioactive compound
KW - fermented foods
KW - functional foods
KW - plant-based foods
KW - probiotics
KW - urinary tract infection
UR - http://www.scopus.com/inward/record.url?scp=105001306441&partnerID=8YFLogxK
U2 - 10.3390/nu17060986
DO - 10.3390/nu17060986
M3 - Review article
AN - SCOPUS:105001306441
SN - 2072-6643
VL - 17
JO - Nutrients
JF - Nutrients
IS - 6
M1 - 986
ER -