Miniaturization in biotechnology: Speeding up the development of bioprocesses

Pedro Fernandes; Filipe Carvalho; Marco P.C. Marques

doi:10.2174/187220811797579105

Miniaturization in biotechnology: Speeding up the development of bioprocesses

Pedro Fernandes, Filipe Carvalho, Marco P.C. Marques

University of Lisbon

Research output: Contribution to journal › Review article › peer-review

29 Citations (Scopus)

Abstract

The use of miniaturized devices for fastening bioprocess development, even up to production scale, has expanded rapidly, a feature clearly noticeable in recent years. This matter was reviewed in a recent past, but several developments have occurred since. These will be addressed in the present work, which will provide some insight on the use of microfluidic /microstructured reactors and of micro-scale downstream processing as well, therefore broadening the scope of the review.

Original language	English
Pages (from-to)	160-173
Number of pages	14
Journal	Recent Patents on Biotechnology
Volume	5
Issue number	3
DOIs	https://doi.org/10.2174/187220811797579105
Publication status	Published - Dec 2011
Externally published	Yes

Keywords

Automation
Biocatalysis
Downstream processing
Fermentation
High throughput
Microfluidic devices
Microreactors
Microsensors
Microstructured reactors
Microtiter plates
Miniature bioreactors
Miniaturization in biotechnology
Monitoring and control of process variables
Optodes
Process intensification
Shaken vessels

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10.2174/187220811797579105

Cite this

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title = "Miniaturization in biotechnology: Speeding up the development of bioprocesses",

abstract = "The use of miniaturized devices for fastening bioprocess development, even up to production scale, has expanded rapidly, a feature clearly noticeable in recent years. This matter was reviewed in a recent past, but several developments have occurred since. These will be addressed in the present work, which will provide some insight on the use of microfluidic /microstructured reactors and of micro-scale downstream processing as well, therefore broadening the scope of the review.",

keywords = "Automation, Biocatalysis, Downstream processing, Fermentation, High throughput, Microfluidic devices, Microreactors, Microsensors, Microstructured reactors, Microtiter plates, Miniature bioreactors, Miniaturization in biotechnology, Monitoring and control of process variables, Optodes, Process intensification, Shaken vessels",

author = "Pedro Fernandes and Filipe Carvalho and Marques, {Marco P.C.}",

year = "2011",

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language = "English",

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AU - Carvalho, Filipe

AU - Marques, Marco P.C.

PY - 2011/12

Y1 - 2011/12

N2 - The use of miniaturized devices for fastening bioprocess development, even up to production scale, has expanded rapidly, a feature clearly noticeable in recent years. This matter was reviewed in a recent past, but several developments have occurred since. These will be addressed in the present work, which will provide some insight on the use of microfluidic /microstructured reactors and of micro-scale downstream processing as well, therefore broadening the scope of the review.

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KW - Automation

KW - Biocatalysis

KW - Downstream processing

KW - Fermentation

KW - High throughput

KW - Microfluidic devices

KW - Microreactors

KW - Microsensors

KW - Microstructured reactors

KW - Microtiter plates

KW - Miniature bioreactors

KW - Miniaturization in biotechnology

KW - Monitoring and control of process variables

KW - Optodes

KW - Process intensification

KW - Shaken vessels

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EP - 173

JO - Recent Patents on Biotechnology

JF - Recent Patents on Biotechnology

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ER -

Miniaturization in biotechnology: Speeding up the development of bioprocesses

Abstract

Keywords

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