Isolation of a biodegradable sterol-rich fraction from industrial wastes

A. C.P. Dias; P. Fernandes; J. M.S. Cabral; H. M. Pinheiro

doi:10.1016/S0960-8524(01)00187-0

Isolation of a biodegradable sterol-rich fraction from industrial wastes

A. C.P. Dias, P. Fernandes, J. M.S. Cabral, H. M. Pinheiro

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

Several industrial waste materials were screened for their sterol content. The possibility of using these industrial by-products as sterol sources for the microbiological production of 4-androsten-3,17-dione (AD) and 1,4-androsta-diene-3,17-dione (ADD) was investigated. Two methods of obtaining the sterol fraction from wastes were developed. Sterol-rich (96-98%) fractions were isolated in a yield above 70%, from a tall-oil effluent of a paper pulp industry and from edible-oil deodorizates. These fractions were subsequently used as a substrate for microbial degradation by a Mycobacterium sp. strain and proved to be easily converted to AD and ADD.

Original language	English
Pages (from-to)	253-260
Number of pages	8
Journal	Bioresource Technology
Volume	82
Issue number	3
DOIs	https://doi.org/10.1016/S0960-8524(01)00187-0
Publication status	Published - 2002

Keywords

4-Androstene-3,17-dione
Biotransformation
Mycobacterium sp.
Oil deodorizates
Sitosterol
Tall-oil

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10.1016/S0960-8524(01)00187-0

Cite this

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AU - Dias, A. C.P.

AU - Fernandes, P.

AU - Cabral, J. M.S.

AU - Pinheiro, H. M.

PY - 2002

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AB - Several industrial waste materials were screened for their sterol content. The possibility of using these industrial by-products as sterol sources for the microbiological production of 4-androsten-3,17-dione (AD) and 1,4-androsta-diene-3,17-dione (ADD) was investigated. Two methods of obtaining the sterol fraction from wastes were developed. Sterol-rich (96-98%) fractions were isolated in a yield above 70%, from a tall-oil effluent of a paper pulp industry and from edible-oil deodorizates. These fractions were subsequently used as a substrate for microbial degradation by a Mycobacterium sp. strain and proved to be easily converted to AD and ADD.

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Isolation of a biodegradable sterol-rich fraction from industrial wastes

Abstract

Keywords

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