Correction: Correction for Pardos de la Gandara et al., "Genetic Determinants of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus" (Antimicrobial agents and chemotherapy (2018) 62 6 PII: e01096-18)

Maria Pardos De La Gandara, Vitor Borges, Marilyn Chung, Catarina Milheiriço, João Paulo Gomes, Herminia De Lencastre, Alexander Tomasz

Research output: Contribution to journalComment/debate

Abstract

Volume 62, no. 6, e00206-18, 2018, https://doi.org/10.1128/AAC.00206-18. The authors note that (i) the gene that was affected in this study, encoding the ribose-phosphate pyrophosphokinase, is associated with different gene designations (prs or prsA) in genome annotations of different Staphylococcus aureus reference strains (as indicated in Table 1) and (ii) two genes (locus_tags SACOL0544 and SACOL1897) encoding different products are annotated as prsA in the genome of reference S. aureus COL strain (CP000046). This nomenclature issue has led to an erroneous description of the gene role in the Discussion section and in Figure 1 as linked to the foldase protein PrsA studied in reference 13 (Jousselin et al., 2015). Therefore, the reader should be aware of the following points: 1. Whenever prsA or PrsA are mentioned in the article, it may also read prs or Prs, respectively. 2. Page 6 of the PDF, 4 th paragraph, the sentence “The chaperone PrsA was recently identified as a new auxiliary factor of oxacillin resistance in MRSA, affecting presumably the posttranscriptional maturation of penicillin-binding protein 2A (PBP2A), possibly at the stage of export and/or folding of newly synthesized PBP2A (13)” should be replaced with “Another target of amino acid replacements in distinct clones (RU-CAMP-28-3, RU-CAMP-28-5, and RU-CAMP-29-2) was the ribose-phosphate pyrophosphokinase (PrsA), which is involved in the direct or indirect production of purine/pyrimidine precursors.”3.Figure 1 should appear as shown below:(figure presented.).

Original languageEnglish
JournalAntimicrobial Agents and Chemotherapy
Volume62
Issue number7
DOIs
Publication statusPublished - Jul 2018
Externally publishedYes

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Copyright © 2018 American Society for Microbiology. All Rights Reserved.

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