Cinnamon: An aromatic condiment applicable to chronic kidney disease

Laís De Souza Gouveia Moreira; Isabela De Souza Brum Da Costa; Drielly C.M. De Vargas Reis; Liana Trugilho; Tuany R. Chermut; Marta Esgalhado; Ludmila F.M.F. Cardozo; Peter Stenvinkel; Paul G. Shiels; Denise Mafra

doi:10.23876/j.krcp.22.111

Cinnamon: An aromatic condiment applicable to chronic kidney disease

Laís De Souza Gouveia Moreira, Isabela De Souza Brum Da Costa, Drielly C.M. De Vargas Reis, Liana Trugilho, Tuany R. Chermut, Marta Esgalhado, Ludmila F.M.F. Cardozo, Peter Stenvinkel, Paul G. Shiels, Denise Mafra

Research output: Contribution to journal › Review article › peer-review

8 Citations (Scopus)

Abstract

Cinnamon, a member of the Lauraceae family, has been widely used as a spice and traditional herbal medicine for centuries and has shown beneficial effects in cardiovascular disease, obesity, and diabetes. However, its effectiveness as a therapeutic intervention for chronic kidney disease (CKD) remains unproven. The bioactive compounds within cinnamon, such as cinnamaldehyde, cinnamic acid, and cinnamate, can mitigate oxidative stress, inflammation, hyperglycemia, gut dysbiosis, and dyslipidemia, which are common complications in patients with CKD. In this narrative review, we assess the mechanisms by which cinnamon may alleviate complications observed in CKD and the possible role of this spice as an additional nutritional strategy for this patient group.

Original language	English
Pages (from-to)	4-26
Number of pages	23
Journal	Kidney Research and Clinical Practice
Volume	42
Issue number	1
DOIs	https://doi.org/10.23876/j.krcp.22.111
Publication status	Published - Jan 2023
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2023 by The Korean Society of Nephrology.

Funding

This study was supported by Conselho Nacional de Desen-volvimento Científico e Tecnológico (CNPq) number 200162/2020-9 and by Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) number E-26/202.524/2019. Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), and Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ)

Funders	Funder number
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Conselho Nacional de Desenvolvimento Científico e Tecnológico	200162/2020-9
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro	E-26/202.524/2019

Keywords

Chronic renal insufficiency
Cinnamomum zeylanicum
Inflammation
Oxidative stress
Spices

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.23876/j.krcp.22.111

Cite this

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title = "Cinnamon: An aromatic condiment applicable to chronic kidney disease",

abstract = "Cinnamon, a member of the Lauraceae family, has been widely used as a spice and traditional herbal medicine for centuries and has shown beneficial effects in cardiovascular disease, obesity, and diabetes. However, its effectiveness as a therapeutic intervention for chronic kidney disease (CKD) remains unproven. The bioactive compounds within cinnamon, such as cinnamaldehyde, cinnamic acid, and cinnamate, can mitigate oxidative stress, inflammation, hyperglycemia, gut dysbiosis, and dyslipidemia, which are common complications in patients with CKD. In this narrative review, we assess the mechanisms by which cinnamon may alleviate complications observed in CKD and the possible role of this spice as an additional nutritional strategy for this patient group.",

keywords = "Chronic renal insufficiency, Cinnamomum zeylanicum, Inflammation, Oxidative stress, Spices",

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doi = "10.23876/j.krcp.22.111",

language = "English",

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T2 - An aromatic condiment applicable to chronic kidney disease

AU - Moreira, Laís De Souza Gouveia

AU - Brum Da Costa, Isabela De Souza

AU - De Vargas Reis, Drielly C.M.

AU - Trugilho, Liana

AU - Chermut, Tuany R.

AU - Esgalhado, Marta

AU - Cardozo, Ludmila F.M.F.

AU - Stenvinkel, Peter

AU - Shiels, Paul G.

AU - Mafra, Denise

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AB - Cinnamon, a member of the Lauraceae family, has been widely used as a spice and traditional herbal medicine for centuries and has shown beneficial effects in cardiovascular disease, obesity, and diabetes. However, its effectiveness as a therapeutic intervention for chronic kidney disease (CKD) remains unproven. The bioactive compounds within cinnamon, such as cinnamaldehyde, cinnamic acid, and cinnamate, can mitigate oxidative stress, inflammation, hyperglycemia, gut dysbiosis, and dyslipidemia, which are common complications in patients with CKD. In this narrative review, we assess the mechanisms by which cinnamon may alleviate complications observed in CKD and the possible role of this spice as an additional nutritional strategy for this patient group.

KW - Chronic renal insufficiency

KW - Cinnamomum zeylanicum

KW - Inflammation

KW - Oxidative stress

KW - Spices

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Cinnamon: An aromatic condiment applicable to chronic kidney disease

Abstract

Bibliographical note

Funding

Keywords

UN SDGs

Access to Document

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Cite this