Abstract
Objective: Describe the existing scientific literature regarding the feasibility and behavior of biodegradable stents (BDSs) in companion animals. Study Design: Systematic scoping review. Methods: A literature search was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) and followed the recommendations of the Cochrane Collaboration. The search was performed by using PubMed, Web of Science, and Scopus databases, focusing on BDS usage in companion animals’ urinary, respiratory, and digestive systems including choledochal duct. Results: In total, 233 articles were identified but only 21 fulfilled the inclusion criteria. Ninety percent (n = 19) of the investigation was conducted in animal models aiming translational to humans, and only two studies involved clinical cases. Regarding application, 42.9% was focused on the urinary system, 19% assessed vascular stenting, 14.3% esophageal stenting, 19% choledochal duct stenting, and 4.8% tracheal stenting. Polylactic acid (PLA) was the most used biomaterial. Conclusion: This review summarized the use of BDS in companion animals, highlighting that most studies were conducted in animals without clinical disease, with most reporting a low incidence of self-limiting complications. Clinical Significance: This review underscores the potential impact of BDS on companion animals. Further research is necessary to explore BDS’s full potential in small animal medicine.
Original language | English |
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Article number | 6405530 |
Pages (from-to) | 6405530 |
Journal | Veterinary Medicine International |
Volume | 2025 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Jan 2025 |
Externally published | Yes |
Bibliographical note
Copyright © 2025 Daiana R. Cardoso et al. Veterinary Medicine International published by John Wiley & Sons Ltd.Funding
This research was supported by the Portuguese Foundation for Science and Technology (FCT) through the projects UIDB/00772/2020 (CECAV, doi: 10.54499/UIDB/00772/2020) and LA/P/0059/2020 (AL4AnimalS). FCT supported Daiana R. Cardoso through a PhD Scholarship (2024.06631.BDANA) and João F. Requicha by the Scientific Employment Stimulus‐Institutional Call (CEECINS/00127/2018).
Funders | Funder number |
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FCT - Fundação para a Ciência e a Tecnologia | UIDB/00772/2020 |
Keywords
- absorbable implants
- animal models
- biomaterials
- interventional urology
- medical devices
- veterinary medicine