An expedient stereoselective synthesis of polysubstituted piperidin-2-ones

M. Teresa Barros; M. Adilia Januário-Charmier; Christopher D. Maycock; Thierry Michaud

doi:10.1016/S0040-4020(02)00015-7

An expedient stereoselective synthesis of polysubstituted piperidin-2-ones

M. Teresa Barros, M. Adilia Januário-Charmier, Christopher D. Maycock, Thierry Michaud

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

A versatile approach to the synthesis of various chiral substituted azido compounds is described. The utility and flexibility of this methodology has been demonstrated by the stereoselective synthesis of optically active polysubstituted piperidin-2-ones which are promising precursors for the synthesis of several indolizidine and piperidine alkaloids.

Original language	English
Pages (from-to)	1519-1524
Number of pages	6
Journal	Tetrahedron
Volume	58
Issue number	8
DOIs	https://doi.org/10.1016/S0040-4020(02)00015-7
Publication status	Published - 18 Feb 2002

Funding

Fundação para Ciência e Tecnologia is acknowledged for a post-doctoral fellowship to T. M. and generous financial support (PCEX/C/QUI/93/96).

Funders	Funder number
Fundação para Ciência e Tecnologia	PCEX/C/QUI/93/96

Keywords

Indolizidine
Piperidin-2-ones
Stereoselective synthesis

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10.1016/S0040-4020(02)00015-7

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abstract = "A versatile approach to the synthesis of various chiral substituted azido compounds is described. The utility and flexibility of this methodology has been demonstrated by the stereoselective synthesis of optically active polysubstituted piperidin-2-ones which are promising precursors for the synthesis of several indolizidine and piperidine alkaloids.",

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T1 - An expedient stereoselective synthesis of polysubstituted piperidin-2-ones

AU - Barros, M. Teresa

AU - Januário-Charmier, M. Adilia

AU - Maycock, Christopher D.

AU - Michaud, Thierry

PY - 2002/2/18

Y1 - 2002/2/18

N2 - A versatile approach to the synthesis of various chiral substituted azido compounds is described. The utility and flexibility of this methodology has been demonstrated by the stereoselective synthesis of optically active polysubstituted piperidin-2-ones which are promising precursors for the synthesis of several indolizidine and piperidine alkaloids.

AB - A versatile approach to the synthesis of various chiral substituted azido compounds is described. The utility and flexibility of this methodology has been demonstrated by the stereoselective synthesis of optically active polysubstituted piperidin-2-ones which are promising precursors for the synthesis of several indolizidine and piperidine alkaloids.

KW - Indolizidine

KW - Piperidin-2-ones

KW - Stereoselective synthesis

UR - http://www.scopus.com/inward/record.url?scp=0037127855&partnerID=8YFLogxK

U2 - 10.1016/S0040-4020(02)00015-7

DO - 10.1016/S0040-4020(02)00015-7

M3 - Article

AN - SCOPUS:0037127855

SN - 0040-4020

VL - 58

SP - 1519

EP - 1524

JO - Tetrahedron

JF - Tetrahedron

IS - 8

ER -

An expedient stereoselective synthesis of polysubstituted piperidin-2-ones

Abstract

Funding

Keywords

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